Research Paper Volume 13, Issue 18 pp 22444—22458

SUV39H2/KMT1B Inhibits the cardiomyocyte senescence phenotype by down-regulating BTG2/PC3

The p53-BTG2 pathways play a role in regulating senescence in SUV39H2-knockdown cardiomyocytes induced by H2O2. (A) Scheme indicating the proposed mechanism of senescence regulation by SUV39H2 in H9C2 cells.

Figure 7. The p53-BTG2 pathways play a role in regulating senescence in SUV39H2-knockdown cardiomyocytes induced by H2O2. (A) Scheme indicating the proposed mechanism of senescence regulation by SUV39H2 in H9C2 cells.