Research Paper Volume 13, Issue 18 pp 22588—22610

GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsis

GPR43 is involved in the activation of NLRP3 inflammasome in sepsis model by ROS-induced mitochondrial damage via PPARγ.

Figure 9. GPR43 is involved in the activation of NLRP3 inflammasome in sepsis model by ROS-induced mitochondrial damage via PPARγ.