Research Paper Volume 13, Issue 21 pp 24117—24135

Integrated analysis of expression, prognostic value and immune infiltration of GSDMs in hepatocellular carcinoma

Predicted functions and pathways of GSDMs and GSDM-associated co-expressed molecules in HCC. (A) 168 GSDM-associated co-expressed molecules which were most frequently altered in HCC were identified by using cBioPortal, and protein-protein interaction (PPI) network was then conducted by Cytoscape. (B) Gene Ontology (GO) functional enrichment analysis of GSDM-associated co-expressed molecules was conducted by WebGestalt. (C) Kyoto Encyclopedia of Genes and Genome (KEGG) pathway analysis of GSDM-associated co-expressed molecules was conducted by WebGestalt.

Figure 5. Predicted functions and pathways of GSDMs and GSDM-associated co-expressed molecules in HCC. (A) 168 GSDM-associated co-expressed molecules which were most frequently altered in HCC were identified by using cBioPortal, and protein-protein interaction (PPI) network was then conducted by Cytoscape. (B) Gene Ontology (GO) functional enrichment analysis of GSDM-associated co-expressed molecules was conducted by WebGestalt. (C) Kyoto Encyclopedia of Genes and Genome (KEGG) pathway analysis of GSDM-associated co-expressed molecules was conducted by WebGestalt.