Research Paper

Pachymic acid ameliorates myocardial ischemia and reperfusion injury by attenuating cardiomyocyte apoptosis through the regulation of the mTOR signal pathway

class="figure-viewer-img"

Figure 2. PA improves mitochondrial function in H/R NMVCs. (A) The ATP content was explored in NMVCs. n=4, *P<0.05, #P<0.05. (B) The ROS production in NMVCs was determined. Scale bar 20 μm. n=4, **P<0.01, #P<0.05. (C) The mPTP opening rate in NMVCs was explored. n=5, **P<0.01, #P<0.05. (D) Mitochondrial membrane potential detection in NMVCs. n=4, *P<0.05, #P<0.05. The level of GSH (E) and GR activity (F) in NMVCs. n=4, **P<0.01, #P<0.05.