Research Paper
Pachymic acid ameliorates myocardial ischemia and reperfusion injury by attenuating cardiomyocyte apoptosis through the regulation of the mTOR signal pathway
Figure 5. PA ameliorates cardiac function in I/R mice. (A) Cardiac function was detected by echocardiography measurement: EF (B) and FS (C). (D) Infarct sizes as the percent of area at risk (AAR). n=4. *P<0.05, #P<0.05. (E) Representative images of TUNEL staining. (F) Respective HE-stained images of hearts. (G) Transmission electron microscopy was used to detect mitochondrial morphology. (H) The apoptosis-associated protein level in cardiac tissues, Cytochrome-c (Cyt-c), Bax, and Bcl2. n=4, *P<0.05, #P<0.05.