Research Paper
Pachymic acid ameliorates myocardial ischemia and reperfusion injury by attenuating cardiomyocyte apoptosis through the regulation of the mTOR signal pathway
Figure 6. PA regulates autophagy in I/R via mTOR/p70SK6 signal pathway. (A, B) The protein level of mTOR and p70S6K in cardiac tissues and NMVCs. n=4, *P<0.05, #P<0.05. (C) The protein level was detected by Western blot. n=4, *P<0.05 vs. Control group, #P<0.05 vs. H/R group, &P<0.05 vs. H/R+PA group. (D) He apoptosis-associated protein level in cardiac tissues, Cytochrome-c (Cyt-c), Bax, and Bcl2. n=4, P<0.05 vs. Control group, #P<0.05 vs. H/R group, &P<0.05 vs. H/R+PA group.