Research Paper
LncRNA FOXN3-AS2 modulated the growth of papillary thyroid carcinoma via miR-34a/SOX4 axis
Figure 4. MiR-34a inhibits PTC development by downregulating SOX4. SOX4 or NC was transfected into TCP-1 cells. (A) The mRNA expression of SOX4 was determined by qRT-PCR, (B) and the protein level of SOX4 was tested by Western blot(*p < 0.05). (C) CKK-8 assay was used to examine the cell growth at 0, 24, 48 and 72 h (*p < 0.05). (D) Colony formation assay was used to calculated cell proliferation (*p < 0.05). (E) Wound healing assay was used to detect cell migration (*p < 0.05). (F) Transwell assay was performed to check cell invasive ability (*p < 0.05).