Research Paper Volume 13, Issue 23 pp 25440—25452

Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function

class="figure-viewer-img"

Figure 3. The expression of BTB-associated proteins in TM-4 cells upon treatment with two different concentrations of TiO2-NPs for 24 h. “3–3”: 30 μg/ml, “3–6”: 60 μg/ml, “3-N”: TM-4 cells were treated with 5 mM NAC for 2 h and then treated with 60 μg/ml 3-nm TiO2-NPs for 24 h. “24–3”: 30 μg/ml, “24–6”: 60 μg/ml, “24-N”: TM-4 cells were treated with 5 mM NAC for 2 h and then treated with 60 μg/ml of 24-nm TiO2-NPs for 24 h. n=5, *p<0.05, **p<0.01 compared to the control; #p<0.05, ##p<0.01 compared to the NPs.