Research Paper
microRNA-212 inhibits nasopharyngeal carcinoma progression through targeting TPD52 and inhibiting EMT and Wnt/β-catenin pathway
Figure 2. MiR-212 overexpression inhibited migration and proliferation of NPC. NC represented C666-1 cells with the negative control sequence. (A) Effect of miR-212 mimics or inhibitor on miR-212 expression in C666-1 cells. N=3. (B) miR-212 mimics or inhibitor influenced cell proliferation in C666-1 cells as detected by MTT assay. N=3. (C, D) miR-212 mimics or inhibitor regulated the migration and invasion of C666-1 cells as detected by Transwell assay. Representative images were shown (Magnification, 40×). Bar graphs indicate mean±SD of 3 independent experiments. (E) Wound healing assay of C666-1 cells transfected with NC, miR-mimics and miR-inhibitor. *p <0.05, **p <0.01.