Research Paper Volume 13, Issue 24 pp 26137—26147
miR-545 promotes colorectal cancer by inhibiting transferring in the non-normal ferroptosis signaling
Figure 6. Inhibition of miR-545 decreased tumor growth in vivo. Inhibition of miR-545 decreased tumor sizes in C57BL/6 mice injected subcutaneously with indicated HT-29 (A) or HCT-116 (B) cells. Inhibition of miR-545 reduced tumor volumes compared to erastin alone for HT-29 (C) and HCT-116 (D) cells. Inhibition of miR-545 further reduced tumor weights compared to erastin alone for HT-29 (E) and HCT-116 (F) cells. *p < 0.05, **p < 0.01, ***p < 0.001 vs. as indicated.