Research Paper Volume 14, Issue 8 pp 3617—3632

Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling

class="figure-viewer-img"

Figure 4. Puerarin inhibits apoptosis of cardiomyocytes in septic mice. (A, B) TUNEL staining was used to measure myocardial apoptosis in myocardial tissue sections. (C, D) Representative Western blot analysis and quantitative protein analysis of C-Caspase 3 expression in cardiac protein extract. (E, F) Representative Western blot analysis and quantitative protein analysis of Bax, and Bcl-2 expression in cardiac protein extract. Data represent the mean ± SD. *P < 0.05 vs Control group; #P < 0.05 vs. LPS group; &P < 0.05 vs. LPS+Pue group.