Research Paper Volume 14, Issue 9 pp 3887—3909

Ox-LDL-mediated ILF3 overexpression in gastric cancer progression by activating the PI3K/AKT/mTOR signaling pathway

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Figure 9. ILF3 promoted tumor cell growth in vivo. (A) Images of nude mouse tumorigenesis test after four weeks of implantation. Comparison of tumor volume between normal diets, high-fat diets, high-fat diets+statin and high-fat diets + ILF3 inhibitor-YM155. Tumors in high-fat diet group were bigger than normal diet group. Tumors in statin and ILF3 inhibitor-YM-155 groups were smaller than high-fat diet group. (B) Immunohistochemistry showed that the expression of ILF3 in normal diets, high-fat diets, high-fat diets+statin and high-fat diets + ILF3 inhibitor-YM155 groups. **P < 0.01, ***P < 0.001, ****P < 0.0001.