Figure 4. Oncomine and ICGC database analysis of MELK in HCC. Oncomine analysis of MELK expression in cancer and normal tissues. (A) Heatmaps showing MELK expression in clinical HCC samples vs. normal tissues. Association between MELK expression and tumor grade (B) and vascular invasion (C) in the Wurmbach Liver dataset. (D) Overall survival analysis of MELK expression in the ICGC database.