Research Paper Volume 14, Issue 9 pp 4036—4049
Pentraxin 3 depletion (PTX3 KD) inhibited myocardial fibrosis in heart failure after myocardial infarction
Figure 6. IL-6 STAT3 signal pathway positively accelerated the fibrotic progression of MI. (A) IL-6 OE significantly increased the fibrotic areas in MI vs model group. (B) Western blot results showed the obvious increased expression of IL-6, p-STAT3, and collagen I/III in IL-6 OE group mice vs Model group mice. *p<0.05, ** p<0.01, *** p<0.001.