Research Paper Volume 14, Issue 11 pp 4769—4785

ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function

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Figure 1. The improving effect of ZQFZ on colorectum and viscus in ApcMin/+ mice. (A) The effect of ZQFZ on the colorectal morphology, black arrows indicated colorectal tumors. (B) The effects of ZQFZ on the number of colorectal tumors (n = 8 mice/group). H&E staining was used to evaluate pathological alterations of (C) colorectum (400×, scale bar: 20 μm), (D) The effects of ZQFZ on organ indexes (n = 6 mice/group), (E) heart, liver, spleen, lung and kidney (400×, scale bar: 20 μm) under a light-microscope digital camera (n = 3 mice/group), black arrows indicated with vacuolar degeneration in the liver and inflammatory cell infiltration in pulmonary alveoli. Data was shown as the mean ± SD and determined via a one-way ANOVA test. **p < 0.01 vs. CTRL group.