Research Paper Volume 14, Issue 11 pp 4839—4857

Identification of biomarkers for immunotherapy response in prostate cancer and potential drugs to alleviate immunosuppression

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Figure 3. Identification of immune-response related genes (IRRGs). (A) Volcano plot of differentially expressed genes between responder and non-responder patient groups. In total, 2758 differentially expressed genes (DEGs) were considered as IRRGs. (B) Expression profiles of the top 30 significant IRRGs in responder and non-responder groups. The enriched KEGG pathways (C) and GO terms (D) of IRRGs were determined using ClusterProfiler.