Research Paper Volume 14, Issue 19 pp 7906—7925

Pseudogene UBE2MP1 derived transcript enhances in vitro cell proliferation and apoptosis resistance of hepatocellular carcinoma cells through miR-145-5p/RGS3 axis

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Figure 3. Depletion of UBE2MP1 enhances HCC cell apoptosis. (A) Cell apoptosis was detected by flow cytometry. The representative histograms demonstrate the apoptosis rate in HepG2 cells. (B) The counting number of the apoptotic cells was significantly increased in HepG2 cells by depleting UBE2MP1 (**P<0.01). The results are means of three independent experiments ±SD. (C) The representative histograms demonstrate the apoptosis rate in Hep3B cells. (D) The counting number of the apoptotic cells was significantly increased in HepG2 cells by depleting UBE2MP1 (**P<0.01). The results are means of three independent experiments ±SD.