Comprehensive analysis of prognostic significance of cadherin (CDH) gene family in breast cancer

Su-Chi Ku; Hsin-Liang Liu; Che-Yu Su; I-Jeng Yeh; Meng-Chi Yen; Gangga Anuraga; Hoang Dang Khoa Ta; Chung-Chieh Chiao; Do Thi Minh Xuan; Fidelia Berenice Prayugo; Wei-Jan Wang; Chih-Yang Wang

doi:doi:10.18632/aging.204357

← Back

Research Paper Volume 14, Issue 20 pp 8498—8567

Comprehensive analysis of prognostic significance of cadherin (CDH) gene family in breast cancer

Figure 6. Expression of cadherin (CDH) family genes in subgroups of breast cancer patients. (A) Gene expression analysis among the stages of CDH genes in a breast cancer (GEPIA2) database. The violin plot displayed comparisons of CDH genes expressions from TCGA dataset of breast cancer. An independent t-test was utilized for p values; p<0.05 meant statistically significant; Pr(>F) <0.05 was based on Student’s t-test. (B) Scarff-Bloom-Richardson (SBR) grading of CDH family genes. Associations between CDH1/2/4/7/11/12/13/15 and SBR grading were analyzed via the bc-GenExMiner dataset. (C) The Nottingham prognostic index (NPI) of CDH family genes. Associations between CDH1/2/4/7/11/12/13/15 and NPI values were analyzed via the bc-GenExMiner dataset.