Research Paper Volume 14, Issue 21 pp 8688—8699

Efficacy of zinc carnosine in the treatment of colorectal cancer and its potential in combination with immunotherapy in vivo

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Figure 8. Pattern diagram showing that ZnC slows the progression of CRC by inhibiting the proliferation, invasion and migration and up-regulates PD-L1 expression via inhibiting miR-570. The combination of ZnC and anti-PD1 therapy is beneficial to synergically increase efficacy of anti-tumor in CRC therapy.