Research Paper Volume 14, Issue 24 pp 10027—10049
High MCM8 expression correlates with unfavorable prognosis and induces immune cell infiltration in hepatocellular carcinoma
Figure 9. Association between MCM8 mRNA expression and immune infiltration in HCC. (A) Estimated fractions of 22 immune cells in each HCC tissue, where different color represented different cell types. (B) The heat map shows the difference in immune cells infiltration between high and low SNRPA expression HCC samples. (C) The comparison of estimated fractions of 22 immune cells between the high and low MCM8 expression samples. (D) Correlation between MCM8 expression and 22 tumor-infiltrating immune cells in HCC using the ssGSEA algorithm. (E) The correlation of MCM8 expression with immune infiltration level of T cells gamma delta (a), Mast cells resting (b), Macrophages M2 (c) and Monocytes (d), Neutrophils (e), T cells CD4 memory activated (f1), Macrophage M0 (g), and T cells follicular helper (h). *P<0.05, **P<0.001, ***P<0.001, ns: no statistically significant.