Research Paper Volume 15, Issue 8 pp 2920—2936

ESM1 promotes angiogenesis in colorectal cancer by activating PI3K/Akt/mTOR pathway, thus accelerating tumor progression

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Figure 4. Relative protein expressions of Cyclin D1 and Cyclin A2 in SW480 and SW620 cells. (A, B) Relative protein expressions of Cyclin D1 and Cyclin A2 in ESM1-NC group, ESM1-mimic group, ESM1-NC + PI3K inhibitor group and ESM1-mimic + PI3K inhibitor group. (C, D) Statistics for Cyclin D1 and Cyclin A2 protein expressions. *p < 0.05 and **p < 0.01 vs. ESM1-NC group.