Research Paper Volume 15, Issue 11 pp 4734—4745

miR-506-3p induces autophagy of renal tubular epithelial cells in sepsis through targeting PI3K pathway

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Figure 3. Overexpression of miR-506-3p could reduce apoptosis and promote proliferation after SA-AKI. (A, B) The results of TUNEL staining assay showed that apoptosis was significantly weakened in the miR-506-3p OE group compared to that in the miR-506-3p NC group. (C) Through CCK8 assay, it was found that the cell proliferative capacity of the miR-506-3p OE group was significantly enhanced compared to that in the miR-506-3p NC group.