Research Paper Volume 15, Issue 11 pp 4906—4925

A spliceosome-associated gene signature aids in predicting prognosis and tumor microenvironment of hepatocellular carcinoma

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Figure 8. Immune infiltration analysis. (A) The estimated fractions of 22 immune cells in each HCC sample using the CIBERSORT algorithm and visualized in a bar plot. (B) The heat map exhibited the differences in the fraction of 22 immune cells between the high-risk score and low-risk score groups. (C) The comparison of estimated fractions of 22 immune cells between the high-risk and low-risk score groups. (D) The correlation between the risk score and 22 tumor-infiltrating immune cells in HCC using the ssGSEA algorithm. (E) The correlation of risk score with immune infiltration level of T cells regulatory (a), Macrophages M0 (b), T cells CD8 (c), Mast cell resting (d), Monocytes (e), B cells naive (f), Macrophages M1 (g), and T cells CD4 memory resting (h).