Research Paper Volume 15, Issue 11 pp 5052—5065

Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism

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Figure 5. Overexpression of SESN1 inhibited ferroptosis in ox-LDL-induced HUVECs. (A) Immunofluorescence was used to detect the iron metabolism in vascular tissues. (B) The expressions of SESN1, P53, P21 and ferroptosis-related proteins were detected by western blot. ***P < 0.001 vs. Control; ##P < 0.01, ###p < 0.001 vs. Ov-NC+Model.