Research Paper Volume 15, Issue 11 pp 5144—5163

Network medicine framework identified drug-repurposing opportunities of pharmaco-active compounds of Angelica acutiloba (Siebold & Zucc.) Kitag. for skin aging

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Figure 2. The proteins of the AAK compounds were congregated in the feature-specific adjacent region of skin aging proteins interactome. (A) AAK compound proteins congregated in feature-specific adjacent region of skin aging proteins interactome; (B) The random expectation of the LCC size indicates that the observed skin aging LCC; (C) Size of the LCC formed by the targets of each AAK compound in the skin aging protein interactome and the corresponding significance (|Z-score|).