Research Paper Volume 15, Issue 11 pp 5190—5214

Identification of neoantigens and immunological subtypes in clear cell renal cell carcinoma for mRNA vaccine development and patient selection

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Figure 6. Immune landscape of ccRCC. (A) Immune landscape of ccRCC. (B) Heat map of two principal components with 28 immune cell signatures. (C) Immune landscape of the subsets of ccRCC immune subtypes. (D) Differential enrichment scores of 28 immune cell signatures in the above subsets. (E, F) The prognostic status of each subset of C1 and C2 separately. (G) Immune landscape of samples from three extreme locations and (H) their prognostic status. *padj < 0.05; **padj < 0.01; ***padj < 0.001.