Research Paper Volume 15, Issue 11 pp 5215—5227

PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma

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Figure 2. The differential mRNA expression between clear cell renal cancer and normal tissue. (A) Heatmap color indicates the differentially expressed genes (DEGs) by analyzing the KIRC data from TCGA database. (B) The volcano plots of DEGs in (A) were visualized. (C, D) GO analysis for enrichment of upregulated (C) and downregulated (D) signaling pathways significantly associated with PUS1 expression in KIRC. (E, F) KEGG analysis for enrichment of upregulated (E) and downregulated (F) signaling pathways significantly associated with PUS1 expression in KIRC.