Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice
Figure 9. Antagomir of miR-31-5p can activate AMPK/SIRT1-dependent signaling to inhibit NLRP3 inflammasome in macrophages and promote the transformation of M1-type macrophages to M2-type macrophages to improve inflammatory response in colitis.