Research Paper Volume 16, Issue 9 pp 8044—8069

Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

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Figure 8. Weighted gene co-expression network analysis (WGCNA) identified cell senescence-related hub genes. (A) One outlier was cut by setting the cut height at 140. (B) Determine the optimal soft threshold of WGCNA by scale independence and average connectivity. (C) Dendrogram and module colors of genes in the WGCNA process. (D) Twelve non-gray modules and their correlation with subtypes. (E) The network of the genes in the brown module.