Research Paper Volume 16, Issue 9 pp 8110—8141

Revealing prognostic insights of programmed cell death (PCD)-associated genes in advanced non-small cell lung cancer

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Figure 3. Cluster analysis of 12 PCD-related genes in TCGA-Advanced NSCLC dataset. (A) Non-negative Matrix Factorization (NMF) clustering of twelve PCD-related genes. The correlation coefficients at k = 2-10 are presented in the Figure. (B) Consistency plot illustrating the stability of NMF clustering results. (C) Kaplan-Meier (KM) survival curves of patients in PCD-related clusters. (D) Gene Ontology (GO) analysis of differential genes between cluster 1 and cluster 2. (E) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of differential genes between cluster 1 and cluster 2. (F) Heatmap displaying the hallmark pathways in different PCD clusters.