Research Paper Volume 17, Issue 7 pp 1810—1833
Co-regulation of Nr1d1 and Pparα in age-related changes of lipid metabolism and its modulation by calorie restriction
Figure 7. PPI network constructed with genes related to circadian rhythm and lipid metabolism and aging-altered DEGs, focusing on Nr1d1 and Ppara. NR1D1 is highly related to several circadian and metabolic regulators, such as Bmal1 (Arntl), Nr1d2, Cry1, Acox1, Cpt2, and Ppara.