Research Paper Volume 17, Issue 7 pp 1810—1833
Co-regulation of Nr1d1 and Pparα in age-related changes of lipid metabolism and its modulation by calorie restriction
Figure 9. Immunohistochemical analysis of Nr1d1 expression in rat liver tissues during aging and CR. Nr1d1 protein expression is elevated in liver sections from aged mice compared to young controls, while CR intervention significantly attenuated this age-associated increase. Representative images of Nr1d1 staining of liver sections from the Young (left), Old (center), and Old-CR groups (right). Scale bar = 100 μm.