Research Paper Volume 17, Issue 7 pp 1834—1851

Sesn-1 is required for lifespan extension during caloric deprivation in C. elegans through inhibition of mTORC1 and activation of autophagy

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Figure 1. C. elegans lifespan extension under CD is modulated by sesn-1. The lifespan of WT and sesn-1(ok3157) nematodes was assessed after plating on control or axenic media.