Research Paper Advance Articles

Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures

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Figure 6. Overview of top potential exosome biomarkers for senescence and aging. (A) Exosome proteins and miRNAs identified as potential biomarkers for secondary senescence (paracrine) and aging. (B) Venn diagram showing overlapping and unique exosome proteins in senescent primary human lung fibroblasts (IMR90) and plasma from aging cohorts. Heatmap showing the top 15 commonly altered proteins in senescent fibroblasts and plasma from aging cohorts.