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The cover features Figure 7 "Summary of exosome-mediated intercellular communication in senescence and aging" from Patel et al.

Volume 17, Issue 8

31 August, 2025
pp 1911—2240

About the Cover

The cover features Figure 7 "Summary of exosome-mediated intercellular communication in senescence and aging" from Patel et al.


Research Perspective

Age-related diseases as a testbed for anti-aging therapeutics: the case of idiopathic pulmonary fibrosis

Alex Zhavoronkov, Dominika Wilczok, Feng Ren, Fedor Galkin,
https://doi.org/10.18632/aging.206301 pp 1911—1928
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Research Papers

Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures

Sandip Kumar Patel, Joanna Bons, Jacob P. Rose, Jessie R. Chappel, Rebecca L. Beres, Mark A. Watson, Corey Webster, Jordan B. Burton, Roland Bruderer, Pierre-Yves Desprez, Lukas Reiter, Judith Campisi, Erin S. Baker, Birgit Schilling,
https://doi.org/10.18632/aging.206292 pp 1929—1965
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Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels

Federica Grosso, Daniela Zanetti, Serena Sanna,
https://doi.org/10.18632/aging.206293 pp 1966—1987
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Models for age-specific estimation of appendicular skeletal muscle mass using the ultrasound-measured rectus femoris muscle thickness

Ga Yang Shim, Jong Bum Kim, Chang Won Won, Jae-Young Lim,
https://doi.org/10.18632/aging.206294 pp 1988—1998
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AI-driven toolset for IPF and aging research associates lung fibrosis with accelerated aging

Fedor Galkin, Shan Chen, Alex Aliper, Alex Zhavoronkov, Feng Ren,
https://doi.org/10.18632/aging.206295 pp 1999—2014
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Age-related trends in amyloid positivity in Parkinson’s disease without dementia

Keiko Hatano, Masashi Kameyama, Masanori Kurihara, Kensuke Ohse, Ryoji Goto, Ryoko Ihara, Mana Higashihara, Renpei Sengoku, Yasushi Nishina, Kazutomi Kanemaru, Yuko Saito, Shigeo Murayama, Atsushi Iwata,
https://doi.org/10.18632/aging.206297 pp 2015—2032
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The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity

Abhishek Guha, Ying Si, Reed Smith, Brijesh K. Singh, Benisa Zogu, Angad Yadav, Katherine A. Smith, Mohamed Kazamel, Nan Jiang, Ritchie Ho, Anna Thalacker-Mercer, Shaida A. Andrabi, Joao D. Tavares Da Silva Pereira, Juliana S. Salgado, Manasi Agrawal, Emina Horvat Velic, Peter H. King,
https://doi.org/10.18632/aging.206298 pp 2033—2062
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Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction

Francesco Neri, Shuyuan Zheng, Mark A. Watson, Pierre-Yves Desprez, Akos A. Gerencser, Judith Campisi, Denis Wirtz, Pei-Hsun Wu, Birgit Schilling,
https://doi.org/10.18632/aging.206299 pp 2063—2078
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What is the clinical evidence to support off-label rapamycin therapy in healthy adults?

Jacob M. Hands, Michael S. Lustgarten, Leigh A. Frame, Bradley Rosen,
https://doi.org/10.18632/aging.206300 pp 2079—2088
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Blood vessel and osteocyte networks concurrently rearrange during bone maturation and decline during aging in the femur of male mice

Mathilde Palmier, Marlène Maître, Hélène Doat, Thierry Lesté-Lasserre, Claudine Boiziau, Delphine B. Maurel,
https://doi.org/10.18632/aging.206302 pp 2089—2112
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DNMT1-mediated SPINT2 expression drives early senescence by suppressing c-Met signaling in human fibroblasts

Min Seok Sim, Hae-Ok Byun, Seongki Min, Jiwon Hong, Su Bin Lim, Kyoung Sook Choi, Gyesoon Yoon,
https://doi.org/10.18632/aging.206303 pp 2113—2125
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Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data

Xueyao Wu, Xunying Zhao, Aaron Ge, Zhitong Han, Can Hou, Yu Hao, Jinyu Xiao, Mengyu Fan, Stephen Burgess, Jiayuan Li, Xia Jiang,
https://doi.org/10.18632/aging.206306 pp 2126—2151
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Longitudinal relationship between social and CVD risk factors in older adults with prediabetes: the HRS 2006-2016

Obinna Ekwunife, Yilin Xu, Raphael Fraser, Jennifer Campbell, Rebekah J. Walker, David Jacobs, Leonard E. Egede,
https://doi.org/10.18632/aging.206308 pp 2152—2166
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A protective role of SRC-1 against aging associated cognitive decline

Hesong Liu, Yongjie Yang, Jonathan C. Bean, Yang He, Hailan Liu, Rambabu Majji, Chen Liang, Nan Zhang, Meng Yu, Longlong Tu, Qingzhuo Liu, Yue Deng, Kristine M. Conde, Na Yin, Mengjie Wang, Yongxiang Li, Junying Han, Sanika Vattakuzhiyil Jossy, Megan Elyse Burt, Hari Krishna Yalamanchili, Chunmei Wang,
https://doi.org/10.18632/aging.206311 pp 2167—2188
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Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model

Yoko Miura, Nadia Milad, Akiho Takata, Satoshi Kanazawa,
https://doi.org/10.18632/aging.206312 pp 2189—2211
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Review

Getting to the heart of sarcopenia and cardiovascular disease

Pouya Nezafati, Pankaj Saxena, Jaishankar Raman, Lionel Hebbard, Craig McFarlane,
https://doi.org/10.18632/aging.206296 pp 2212—2239
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Correction

Correction for: Posttranscriptional regulation of AKT by circular RNA angiomotin-like 1 mediates chemoresistance against paclitaxel in breast cancer cells

Jian Ma, Ling Fang, Qi Yang, Steven Hibberd, William W. Du, Nan Wu, Burton B. Yang,
https://doi.org/10.18632/aging.206315 pp 2240
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Volume 17, Issue 8  
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