Research Paper Advance Articles

Figure 3. Impaired LTP in hippocampal CA1 neurons of SRC-1-KO mice. (A) Typical EPSC traces before (lighter curve) and after (darker curve) LTP induction in CA1 neurons from WT or SRC-1-KO mice. (B) Magnitude of EPSC elevations before (0–5 min) and after LTP induction (5–50 min). (C) Averaged EPSC elevations during 45–50 min in (B). N = 5-6 neurons from 3 mice. ^**P < 0.01 in unpaired two-tailed t-tests.