Research Paper Advance Articles

Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity

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Figure 5. Exercise capacity and muscle oxidative function young normal chow (YNC), old normal chow (ONC), young Endocalyx treatment (YEC), and old Endocalyx treatment (OEC) mice. (A) Running time to exhaustion during maximal treadmill test at Week 0 and Week 10. (B) Work performed during maximal treadmill test at Week 0 and Week 10. (C) Gastrocnemius muscle citrate synthase activity. Data are presented as mean ± SEM. *P < 0.05 vs. YNC; P < 0.05 vs. ONC; P < 0.05 vs. YEC; §P < 0.05 vs. Week 0. N = 7–13/group.