Figure 1.Identification of TM4SF1 as a candidate surface marker of senescent pancreatic β-cells. (A) Fluorescence-activated cell sorting (FACS) was used to isolate potential candidates for a tissue-specific pancreatic β-cell senescence cell-surface marker. TM4SF1 highest expression in pancreas. (B) Heatmap of TM4SF1 and PLAUR across tissues in humans. Data obtained from the Human Protein Atlas. (C) Graphical display for genome sequence alignment between Human and Mouse for the TM4SF1 gene.
