Press Releases
2024 Press Releases
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Accelerated Aging in Young Sickle Cell Patients Linked to Elevated T-cell p16INK4a
12-11-2024“These initial results suggest that individuals with SCD have a significantly higher cellular senescence burden which may contribute to premature aging, physiological decline, and excess morbidities.”
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BUFFALO, NY- December 11, 2024 – A new research paper was published …
Prostaglandin E2's Role in Senescence and Neoplastic Escape in Human Keratinocytes
12-10-2024“Our data indicate that the PTGS2 level and the production of PGE2 are increased during in vitro senescence of NHEKs, as well as during aging of skin epidermal keratinocytes.”
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BUFFALO, NY- December 10, 2024 – A new research paper was published in Aging (listed by …
Effects of Megakaryocyte Conditioned Media on Endothelial Cell Angiogenesis
12-04-2024“With aging, the risk of fractures and compromised healing increases.”
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BUFFALO, NY- December 4, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21 on November 22, …
Sleep Deprivation in Dementia: Heart Disease, Diabetes, Anxiety, and Thyroid Disorders
12-02-2024"Sleep disturbances are a significant concern in individuals with dementia, affecting their overall health and quality of life, as well as that of their family members and caregivers.”
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BUFFALO, NY- December 2, 2024 – A new review was published on the cover of Aging …
Nucleoporin93: A Silent Protector in Vascular Health
11-26-2024"Research in the last several decades has established endothelial cells (ECs) as a dynamic interface critical for vascular protection.”
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BUFFALO, NY- November 26, 2024 – This editorial was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …
Phenotypic and Epigenetic Clocks for Aging and Mortality
11-20-2024“Biological clocks are used to measure the aging process in the hopes of identifying possible interventions.”
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BUFFALO, NY- November 20, 2024 – This review was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), in Volume …
Brain Aging and Alzheimer’s: Insights from Non-Human Primates
11-19-2024“Brain aging is a biological process that comprehends degenerative, adaptive, and regenerative brain changes that elapse through maturity until the elderly.”
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BUFFALO, NY- November 19, 2024 – A new review was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
EphA2 Signaling in Eye Lens Aging: Wild-Type, Knockout, and Aging Mice
11-13-2024“Erythropoietin-producing hepatocellular carcinoma (Eph) receptors make up the largest family of human receptor tyrosine kinases (RTKs).”
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BUFFALO, NY- November 13, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Validating an Electronic Frailty Index in a National Health System
11-12-2024“The classification of patients according to their level of frailty allows us to adjust prevention programs and focus our limited resources on the right action for the right person.”
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BUFFALO, NY- November 12, 2024 – A new research paper was published in Aging (listed by …
Impact of Iron on Aging in Enchytraeus crypticus
11-06-2024"[...] the effects on aging as observed are due to the toxicity of Fe ion released and not on a perturbation of the aging mechanism alone.”
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BUFFALO, NY- November 6, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Werner Syndrome RECQ Helicase and Heterochromatin Maintenance in Human Cells
11-05-2024“Our study highlights WRN as a contributor to the integrity of CH and points at the altered levels and distribution of LBR as a mediating mechanism.”
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BUFFALO, NY- November 5, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Longevity Biotechnology: AI, Biomarkers, Geroscience & Applications for Healthy Aging
10-31-2024“The integration of artificial intelligence (AI), biomarkers, ageing biology, and longevity medicine stands as a cornerstone for extending human healthy lifespan.”
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BUFFALO, NY- October 31, 2024 – A new research paper was published on the cover of Aging (listed by …
Cardiovascular Risk Biomarkers in Inflammaging
10-29-2024“Here, we advocate for a more comprehensive biomarker-based approach to CV risk that incorporates two distinct dimensions.”
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BUFFALO, NY- October 29, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
New Model to Study Macrophage Aging Mechanisms
10-24-2024"This model is a valuable tool for characterizing macrophage aging mechanisms and developing innovative strategies with promising therapeutical purpose in limiting inflammaging and ARD.”
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BUFFALO, NY- October 24, 2024 – A new research paper was published in Aging (listed …
Senolytics Dasatinib and Quercetin for Prevention of Pelvic Organ Prolapse in Mice
10-22-2024“This study represents one of the first to evaluate the impact of senolytic agents D+Q on the clinical development of pelvic organ prolapse and expression of proteins associated with cellular senescence in a mouse model.”
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BUFFALO, NY- October 22, 2024 – A new research …
Tribute to Dr. Mikhail (Misha) Blagosklonny
10-22-2024
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It is with great sadness and heavy heart that we announce the recent passing of Dr. Mikhail (Misha) V. Blagosklonny, our beloved Editor-in-Chief. Misha succumbed to metastatic lung cancer after a courageous battle.
Dr. Blagosklonny will be remembered as a brilliant and …
Fibroblast Growth Factor 21 and Survival in the Elderly: Polsenior2 Study Results
10-17-2024“Of note, participants with high serum levels of FGF21 more frequently had metabolic complications, such as hypertension, obesity, diabetes, hypercholesterolemia, and hypertriglyceridemia.”
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BUFFALO, NY- October 17, 2024 – A new research paper was published in Aging …
Proteomics of Bone Formation in Young-Adult and Old Mice
10-15-2024“We conclude that proteomics is a promising approach to study bone biology and detect protein-specific changes in aging.”
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BUFFALO, NY- October 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Cerebral Blood Flow and Arterial Transit in Older Adults
10-08-2024“ATT may be more sensitive to age-related decline than CBF, and therefore useful for early detection and management of cerebrovascular impairment.”
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BUFFALO, NY- October 8, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …
Frailty Linked to Long-term Physical Decline in Cancer Survivors
10-02-2024“Our study highlights the high prevalence of frailty in survivors with detrimental effects on physical and overall wellbeing, and supports an association between frailty and the senescence marker p16INK4a.”
BUFFALO, NY- October 2, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging …
Single Housing Extends Adult Lifespan in African Turquoise Killifish
09-30-2024“The whole-life history traits might be influenced by the degree of early-life cohabitation with others.”
BUFFALO, NY- September 30, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 18 on September 16, …
Sleep Quality, Dementia and Mortality in Older US Adults
09-25-2024“Approximately 20% of adults are impacted by health issues associated with substandard sleep quality or insufficient sleep durations.”
BUFFALO, NY- September 25, 2024 – A new research paper titled, “Poor sleep quality, dementia status and their association with all-cause mortality among older US adults” was published …
Intraovarian PRP Improves Oocyte Quality and Embryo Development in Mouse Models
09-24-2024“Ovarian aging is associated with a progressive physiological decline in the quantity and quality of the oocytes.”
BUFFALO, NY- September 24, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 13, 2024, …
Activity Monitoring and Lifespan: A Longitudinal Study
09-18-2024“We specifically demonstrate the methodology with data on activity monitoring for Mediterranean fruit flies.”
BUFFALO, NY- September 18, 2024 – A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 9, 2024, …
The Cell Rejuvenation Atlas: Identifying Master Regulators of Rejuvenation Strategies
09-16-2024“Thus, we expect SINGULAR to be of great utility in informing further advances in human age reversal.”
BUFFALO, NY- September 16, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 9, 2024, …
Leukocyte Telomere Length and Disease Severity in Cystic Fibrosis
09-11-2024“We hypothesized that CF patients with more severe disease characteristics exhibit shorter leukocyte telomere length (LTL) and greater LTL attrition.”
BUFFALO, NY- September 11, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume …
2-Bromopalmitate Reduces Senescence in Human Cells: Role of Palmitoylation
09-10-2024“For the first time, the present study revealed a critical role for protein palmitoylation in the development of a DNA damage-induced senescence phenotype.”
BUFFALO, NY- September 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), V…
Effects and Consequences of Cardiac Metabolism in the Elderly
09-04-2024“We aim to explore the relationship between cardiac metabolism dysfunction and heart failure, emphasizing the need of innovative treatments to manage these interconnected cardiovascular conditions.”
BUFFALO, NY- September 4, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …
Proteomic and Secretomic Analysis Reveals Cytoskeleton's Role in Aging
09-03-2024“Our present data reinforce knowledge about an age-related alteration in the synthesis of major proteins linked to the migratory and contractile functions of dermal human fibroblasts.”
BUFFALO, NY- September 3, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Trioxidized Cysteine and Aging: Beyond Proteinopathic Paradigms
08-27-2024“The results indicated a significant increase in cumulative t-Cys levels and the total number of t-Cys residues in aging and aged mice proteomes compared to young groups.”
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BUFFALO, NY- August 27, 2024 – A new research perspective was published in Aging (listed by …
Impact of Exercise on Aging: Highlighting Muscle Biomarkers
08-21-2024“Here, we presented the first quantitative and qualitative study on the effect of exercise on age-related biomarkers in human skeletal tissues."
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BUFFALO, NY- August 21, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
How Physical Fitness and Lifestyle Impact Biological Aging
08-20-2024“Here, we discuss our recent report on the ‘Associations between cardiorespiratory fitness and lifestyle-related factors with DNA methylation-based ageing clocks in older men: WASEDA’S Health Study.’”
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BUFFALO, NY- August 20, 2024 – A new editorial was published in Aging …
Cell Death Types and Their Relations to Host Immune Pathways
08-16-2024“We have proposed a framework encompassing all discovered host immunological pathways, such as TH1, TH2a, TH2b, TH3, TH9, TH17, TH22, TH1-like, and THαβ immune reactions”
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BUFFALO, NY- August 16, 2024 – A new review was published as the cover paper of Aging (listed by …
Recalibrating Principles of Epigenetic Aging Clocks in Human Health
08-14-2024“Our study revealed that the composition of immune cells significantly affects the variation in EAA across six common blood epigenetic clocks."
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BUFFALO, NY- August 14, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Lipid Accumulation Drives Cellular Senescence in Dopaminergic Neurons
08-13-2024"These findings align with our previous results in dopaminergic neurons in highlighting a central role for lipid accumulation in the senescence of DA neurons."
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BUFFALO, NY- August 13, 2024 – A new research perspective was published in Aging (listed by MEDLINE/PubMed as …
mTORC1 in Classical Monocytes: Links to Human Size Variation & Neuropsychiatric Disease
08-07-2024"This report suggests that a simple assay may allow cost-effective prediction of medication response."
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BUFFALO, NY- August 7, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, …
Targeted Cancer Therapy: Initial High Concentration May Slow Down Selection for Resistance
08-06-2024“Unfortunately, any targeted therapy is, always, started with low levels of the drug in the organism, selecting for drug resistance.”
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BUFFALO, NY- August 6, 2024 – On July 28, 2024, Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center …
Association Between Osteoporosis and Telomere Shortening
08-05-2024“We sought to identify an association between osteoporosis and LTL shortening in an independent prospective cohort.”
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BUFFALO, NY- August 5, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by …
Co-analysis of Methylation Platforms for Signatures of Biological Aging in the Domestic Dog
07-23-2024“In this study, we explore the potential of the three largest, publicly available DNA methylation datasets in dogs to identify signals of biological age.”
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BUFFALO, NY- July 23, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Modulating Lung Fibroblast Activation via Senolysis of Senescent Human Alveolar Epithelial Cells
07-17-2024“Novel senomorphic and senolytic agents can be evaluated in this model as they are identified.”
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BUFFALO, NY- July 17, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue …
Roles of PEDF in Exercise-induced Suppression of Senescence and its Impact on Lung Pathology in Mice
07-15-2024“[...] the present results strongly suggest the potential of PEDF as a myokine linking exercise training to the suppression of senescence.”
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BUFFALO, NY- July 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Aging Exacerbates Oxidative Stress and Liver Fibrosis in Animal Model of Down Syndrome
07-10-2024“[...] our results put the basis for the use of antioxidants supplementation in Down Syndrome patients to prevent liver-associated pathologies.”
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BUFFALO, NY- July 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Omics-based Insights Into Vision Decline
07-09-2024“These findings potentially support employing anti-aging therapies such as senolytic pharmacologic compounds to prevent or ameliorate progression to AMD [...]”
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BUFFALO, NY- July 9, 2024 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging …
A New Concept Towards an Immune Response Against Cancer and Aging: Senescent Cell-derived Vaccines?
07-01-2024“[...] cancer immunotherapy based on tumor-associated senescent cells and other types of senescent cells may achieve exciting outcomes beyond cancer therapy.”
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BUFFALO, NY- July 1, 2024 – A new review paper was published on the cover of Aging (listed by MEDLINE/PubMed as …
Editorial: Global Consensus for Sarcopenia
06-26-2024“[...] the development of a global conceptual definition of sarcopenia signifies a new dawn for this muscle disease.”
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BUFFALO, NY- June 26, 2024 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Associations of Childhood, Adolescence, and Midlife Cognitive Function With Age Acceleration in Midlife
06-25-2024“[...] our study brings attention to the potential influence of adolescent crystalized intelligence on age-related DNAm at older age.”
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BUFFALO, NY- June 25, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …
Dietary Sucrose Determines Activity of Lithium on Gene Expression and Lifespan in Drosophila Melanogaster
06-19-2024“[...] we found that, in female D. melanogaster, the life-prolonging effect of dietary lithium is dependent on the actual sucrose content of the medium.”
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BUFFALO, NY- June 19, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Mitophagy and Cancer: BNIP3/BNIP3L’s Role in Stemness, ATP Production, Proliferation, and Cell Migration
06-17-2024“[...] our current work has provided a novel strategy to enrich for a sub-population of cancer cells, with high basal levels of mitophagy.”
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BUFFALO, NY- June 17, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany …
The Aging Brain and Peripheral Vascular Dysfunction
06-12-2024“[...] the associations between common non-invasive measures of cardiovascular health (e.g., blood pressure) and risk of dementia are not well-established.”
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BUFFALO, NY- June 12, 2024 – A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
CCR4-NOT in Stress Resistance and Longevity in C. elegans
06-11-2024“[...] it appears that the CCR4-NOT complex can influence longevity in a multitude of manners [...]”
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BUFFALO, NY- June 11, 2024 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, …
Aging Sponsors 2024 Ride for Roswell
06-11-2024Impact Journals (Aging's publisher) is sponsoring Team Open Access in the annual cycling event to end cancer: The Ride for Roswell. This fundraiser is hosted by Roswell Park Comprehensive Cancer Center in Buffalo, New York.
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BUFFALO, NY- June 11, 2024 – The Ride for …
Depression, Antidepressants, Epigenetic Age Acceleration, and Mortality in Postmenopausal Women
06-10-2024“The study examined the impact of depressive symptoms, antidepressant use, and epigenetic age acceleration on all-cause mortality in postmenopausal women.”
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BUFFALO, NY- June 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging …
Serine Racemase Expression in the Brain During Aging in Male and Female Rats
06-05-2024“The findings of the present study reveal that aging is linked to a decline in serine racemase protein levels across various brain regions [...]”
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BUFFALO, NY- June 5, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Proteomics Uncover Sexual Dimorphism and Immune Changes in Aging Werner Syndrome Mice
06-03-2024“Proteomics analysis at different ages allows us to follow the progressive biological alterations (including histological fat accumulation) in the liver according to age and/or the Wrn genotype.”
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BUFFALO, NY- June 3, 2024 – A new research paper was published on the cover …
Modulation of Senescence Features Using Weo Electrolyzed Water
05-22-2024“[...] Weo electrolyzed water could have a positive impact on longevity and age-related diseases.”
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BUFFALO, NY- May 22, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 9…
Germicidal Lamps Using UV-C Radiation May Pose Health Safety Issues
05-21-2024“Despite the potential advantages of utilizing UV-C radiation for deactivating pathogens such as SARS-CoV-2, the prevailing conclusion remains that UV-C radiation poses concurrent risks to human health.”
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BUFFALO, NY- May 21, 2024 – A new research paper was published in Ag…
Aging Contributes to 2024 Systems Aging Gordon Research Conference
05-20-2024Aging is contributing at the 2024 Systems Aging Gordon Research Conference in Barcelona, Spain, from June 2–7.
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BUFFALO, NY- May 20, 2024 – Aging is a contributor at the 2024 Systems Aging Gordon Research Conference (GRC) on “Systems Modeling, Aging Biomarkers, and …
Age-associated Gene Expression Changes in Mouse Sweat Glands
05-14-2024“In this study, we first obtained evidence that, in mouse, aging primarily reduced the number of active sweat glands.”
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BUFFALO, NY- May 14, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Aging at SSP 46th Annual Meeting
05-13-2024Aging is proud to participate at the Society for Scholarly Publishing (SSP) 46th Annual Meeting, which convenes May 29–31, 2024, in Boston, Massachusetts.
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BUFFALO, NY- May 13, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences, with a focus on …
The Beginning of Becoming a Human: A Review
05-09-2024“Debates on when human life begins are rooted deep in philosophical history. However, until recently they have been limited by the state of technology.”
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BUFFALO, NY- May 9, 2024 – A new review paper was published in advance by Aging (listed by MEDLINE/PubMed as "Aging …
Association Between Neighborhood Deprivation and DNA Methylation in an Autopsy Cohort
05-08-2024“[...] our study identified one CpG site (cg26514961, PLXNC1 gene) that was significantly associated with neighborhood deprivation in brain tissue.”
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BUFFALO, NY- May 8, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …
Association of Inflammatory and Metabolic Biomarkers and Accelerated Aging in Cardiac Catheterization Patients
05-07-2024“[...] this study is an initial examination of the associations between epigenetic and transcriptomic aging biomarkers and novel NMR lipoprotein biomarkers.”
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BUFFALO, NY- May 7, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging …
A Novel Deep Proteomic Approach Unveils Molecular Signatures Affected by Aging and Resistance Training
05-01-2024“Resistance training can reverse certain aspects of skeletal muscle aging.”
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BUFFALO, NY- May 1, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, “A novel …
Cover Paper: Senescent Characteristics of Human Corneal Endothelial Cells Upon UV-A Exposure
04-30-2024“[...] these findings may help to advance our understanding of the pathogenesis of corneal endothelial disease and may lead to the discovery of new therapies targeting senescent cells.”
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BUFFALO, NY- April 30, 2024 – A new research paper was published on the cover of Aging…
Identifying Proteins Causally Related to COVID-19, Healthspan and Lifespan
04-24-2024“[...] we identified multiple proteins affecting COVID-19 and aging.”
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BUFFALO, NY- April 24, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 7, entitled, “Using …
The Coupling Between Healthspan and Lifespan in Caenorhabditis Depends on…
04-23-2024“The ultimate goal of exploiting model organisms to screen for anti-aging interventions is to identify treatments that might translate to healthy lifespan extension in humans.”
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BUFFALO, NY- April 23, 2024 – A new research paper was published in Aging (listed by …
Longevity & Aging Series: Season 2 Premiere Episode
04-22-2024The Longevity & Aging Series launched its second season with a premiere episode featuring Dr. Irina Conboy and Xiaoyue (Serafina) Mei from the University of California, Berkeley.
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BUFFALO, NY- April 22, 2024 – The Longevity & Aging Series is an enlightening and …
The Impact of Ketogenic Diets on Cognitive Behavior, Motor Function, and Blood Lipids
04-17-2024“[...] intermittent ketogenic diet (IKD) or ketogenic diet (KD) intervention did not improve measures of cognitive or motor behavior in TgF344-AD rats; however, both IKD and KD positively impacted circulating lipids.”
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BUFFALO, NY- April 17, 2024 – A new research paper …
Cover Paper: Evidence of a Pan-tissue Decline in Stemness During Human Aging
04-15-2024“[...] as far as we know, we are the first to provide evidence of [stem cell depletion in aging] in a pan-tissue manner.”
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BUFFALO, NY- April 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Geraniol Attenuates Oxidative Stress and Cognitive Impairment in Mouse Aging Model
04-10-2024“Our data demonstrated, for the first time, the antioxidant activity of geraniol and its function to attenuate brain hippocampus injury induced in vivo by D-galactose.”
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BUFFALO, NY- April 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as …
CMS121 Mitigates Aging-related Obesity and Metabolic Dysfunction
04-09-2024“[...] CMS121 applicability could be expanded from a geroneuroprotector drug to a metabolic drug [...]”
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BUFFALO, NY- April 9, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, …
Does Methylene Blue or Mitoquinone Improve Skeletal Aging?
04-03-2024“[...] long-term administration of MB or MitoQ did not have an effect on skeletal morphology during the aging process [...]”
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BUFFALO, NY- April 3, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Altered Brain Morphology and Functional Connectivity in Postmenopausal Women
04-01-2024“[...] our findings suggest that diminished brain volume and functional connectivity may be linked to menopause-related symptoms caused by the lower sex hormone levels.”
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BUFFALO, NY- April 1, 2024 – A new research paper was published on the cover of Aging (listed by …
Chlorogenic Acid Prevents Ovariectomized-induced Bone Loss
03-26-2024“[...] chlorogenic acid appears to be a promising candidate for the management of osteoporosis.”
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BUFFALO, NY- March 26, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5…
FoxO6-mediated ApoC3 Upregulation Promotes Hepatic Steatosis and Hyperlipidemia in HFD Aged Rats
03-20-2024“This discovery unveils a potential novel molecular target for therapeutic strategies against hepatic steatosis during the aging process [...]”
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BUFFALO, NY- March 20, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
PR55α-controlled PP2A Inhibits p16 Expression and Blocks Cellular Senescence Induction
03-19-2024“Our results show that PR55α specifically reduces p16 expression [...]”
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BUFFALO, NY- March 19, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, “PR55α-contro…
Age Prediction Models in the Human Brain: Genome-wide Transcriptome Profiling and Development
03-15-2024“Our approach identified genes that were previously implicated in aging, as well as new ones that may warrant further investigation.”
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BUFFALO, NY- March 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …
Transcriptomic Modulation of Alzheimer’s Disease by Activated Protein C Using Single-Cell RNA-Seq
03-13-2024“We believe our study utilizing Single-Cell RNA sequencing will provide additional rationale towards the effects on APC treatment observed in previous studies on 5xFAD AD mice.”
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BUFFALO, NY- March 13, 2024 – A new research paper was published in Aging (listed by …
Association of Prenatal Vitamins and Metals With Epigenetic Aging at Birth and in Childhood
03-12-2024“[...] our findings support the hypothesis that the intrauterine environment, particularly essential and non-essential metals, affect epigenetic aging biomarkers across the life course.”
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BUFFALO, NY- March 12, 2024 – A new research paper was published in Aging (listed by …
Aging at AACR Annual Meeting 2024
03-11-2024Aging is proud to participate at the American Association for Cancer Research (AACR) Annual Meeting 2024, which convenes April 5-10 in San Diego, California.
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BUFFALO, NY- March 11, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a …
A Longitudinal Study on Dasatinib, Quercetin, and Fisetin Senolytic Interventions
03-06-2024“[...] our findings underscore the imperative for additional markers to gauge the physiological impact of senolytic treatments [...]”
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BUFFALO, NY- March 6, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …
A Call for Standardization of Controls in Lifespan Studies
03-05-2024“[...] we posit that the majority of results in biology of aging may be irrelevant to the fundamental aim of this field and must be acknowledged appropriately.”
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BUFFALO, NY- March 5, 2024 – A new research perspective was published in Aging (listed by MEDLINE/PubMed as …
Mapping the Core Senescence Phenotype of Human Colon Fibroblasts
02-29-2024“[...] despite the impact of aging on colon health and colon cancer, an atlas of the SASP produced by colon fibroblasts has not been established.”
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BUFFALO, NY- February 29, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as …
Prognostic Model Development and Molecular Subtypes Identification in Bladder Urothelial Cancer
02-28-2024“Our study introduces an oxidative stress-based prognostic model for bladder cancer, offering insights into personalized therapy.”
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BUFFALO, NY- February 28, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …
The Anti-aging Effect of Vitamin D and its Receptor in Drosophila Midgut
02-27-2024“Our study demonstrated that the VitD/VDR [vitamin D/vitamin D receptor] pathway is required for intestinal homeostasis during normal differentiation and aging.”
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BUFFALO, NY- February 27, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as …
Disruption of Mitochondrial Unfolded Protein Response Results in Shortening of Telomeres in Mouse Oocytes and Somatic Cells
02-21-2024“[...] our findings provide a preliminary understanding of how mitochondrial and telomeric aging mechanisms may interact to accelerate reproductive and somatic aging.”
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BUFFALO, NY- February 21, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed …
New Study: Defining the Progeria Phenome
02-20-2024“In sum, we have defined what a premature aging disease is and developed tools to allow diagnostics of patients and disease population.”
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BUFFALO, NY- February 20, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
GV1001 Reduces Neurodegeneration and Prolongs Lifespan in Mouse Model of Alzheimer’s Disease
02-15-2024“[...] accelerated aging and Alzheimer’s disease are closely related, and this study confirmed that GV1001 has multiple anti-aging effects.”
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BUFFALO, NY- February 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging …
IL-17 Promotes IL-18 Production in Osteoarthritis Synovial Fibroblasts Via…
02-13-2024“This study provides novel insights into the pathogenesis of OA and suggests a potential therapeutic target in OA treatment.”
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BUFFALO, NY- February 13, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by …
PROX1/α-SMA Correlated With Colorectal Cancer Progression, Poor Outcomes and Therapeutic Resistance
02-07-2024“The findings validate the combined PROX1/α-SMA gene set as a prospective prognostic biomarker and a central regulator in CRC progression and its TME.”
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BUFFALO, NY- February 7, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Epigenetic Drift Underlies Epigenetic Clock Signals, but…
02-06-2024“In this study, we report an approach for spatially resolving genomic patterns of DNA methylation disorder [...]”
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BUFFALO, NY- February 6, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …
Prognostic Significance of Senescence-related TME Genes in Head and Neck Squamous Cell Carcinoma
01-31-2024“These findings provided evidence for the role of senescence in the tumor microenvironment [...]”
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BUFFALO, NY- January 31, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Vo…
XRCC1: A Potential Prognostic and Immunological Biomarker in Low-Grade Gliomas
01-30-2024“We conducted a comprehensive investigation into the potential of XRCC1 as a valuable diagnostic and prognostic indicator in diverse cancer types."
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BUFFALO, NY- January 30, 2024 – A new research paper was published inAging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …
Targeting FSP1 Regulates Iron Homeostasis in Drug-tolerant Persister Head and Neck Cancer Cells
01-24-2024“Targeting FSP1 is suggested as a new approach in the paradigm shift of treating HNSCC.”
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BUFFALO, NY- January 24, 2024 – A new research paper was published inAging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, …
Systematic Analysis of the Prognostic Value and Immunological Function of LTBR in Cancer
01-23-2024“[...] we identified LTBR as a potential target for cancer immunotherapy and a marker of immune infiltration and poor prognosis.”
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BUFFALO, NY- January 23, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …
Aberrant RBMX Expression Relevant for Cancer Prognosis and Immunotherapy Response
01-17-2024“In the future, targeting of RBMX may be a novel method in cancer therapy.”
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BUFFALO, NY- January 17, 2024 – A new research paper was published inAging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, “Aberran…
Effects of Resveratrol on Circadian Clock Gene Expression in Young and Older Human Cells
01-15-2024“This study reflects transdisciplinary efforts to link aging and circadian biology in human-derived tissues, which is an understudied area of biology.”
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BUFFALO, NY- January 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as …
Clonal Hematopoiesis and Its Impact on Aging, Cancer, and Patient Care
01-10-2024“Understanding the influence of prior treatments on CH [clonal hematopoiesis] dynamics is crucial for comprehending the intricate interplay between therapy, aging, and cancer.”
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BUFFALO, NY- January 10, 2024 – A new editorial paper was published in Aging (listed by …
Systemic Changes Induced by ASCOT in Plasma Proteome of Women With Impaired Ovarian Reserves
01-09-2024“Identifying plasma proteins that regenerate aged or damaged ovaries could lead to more effective, targeted and/or preventive therapies for patients.”
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BUFFALO, NY- January 9, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …
Mapping the Gene Network That Regulates the Glycan Clock of Ageing
01-03-2024“[...] we were able to confirm the functional role of three genes (MANBA, TNFRSF13B and EEF1A1) in the IgG galactosylation pathway [...]”
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BUFFALO, NY- January 3, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …
Age-related Alterations in the Oscillatory Dynamics Serving Verbal Working Memory
01-02-2024“[...] we discuss the implications of these novel findings on our understanding of how healthy aging affects verbal working memory processing.”
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BUFFALO, NY- January 2, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging …