Press

Aging-US: COVID-19 and chronological aging: anti-aging drugs for treatment or prevention

04-20-2020

Volume 12, Issue 8 of @AgingJrnl reported that similarly, two proposed therapeutics for the treatm...

Read More

Scientist proposes clinical trials w/ low-dose rapamycin to protect elderly from COVID-19

04-03-2020

Friday, 3rd of April, 2020, London, UK - The Biogerontology Research Foundation, a registered UK charity supporting and promoting aging and longevity research worldwide since 2008, today announced the publicat...

Read More

Female adipose tissue has improved adaptability and metabolic health compared to males in aged obesity

02-13-2020

Aging-US Volume 12, Issue 2 reported that Younger females are protected from adipose inflammation, but older post-menopausal females exhibit exaggerated visceral adip...

Read More

Rapamycin for longevity- opinion article

10-14-2019

The scientist discusses several reasons, including fear of the actual and fictional side effects of rapamycin, everolimus and other clinically-approved drugs, arguing that no real side effects preclude their use as an...

Read More

Subunit contribution to NMDA receptor hypofunction and redox sensitivity of hippocampal synaptic transmission during aging

10-06-2019

The researchers examined the contribution of N-methyl-D-aspartate receptor subunits in the redox-mediated decline in NMDAR function during aging.

Glu N2A and Glu N2B selective antagonists decreased peak NMDAR c...

Read More

Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan

10-05-2019

Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies.

The researchers found that both males and females demonstrated decreased explo...

Read More

Habitual tea drinking modulates brain efficiency: evidence from brain connectivity evaluation

10-04-2019

The researchers recruited healthy older participants to two groups according to their history of tea drinking frequency and investigated both functional and structural networks to reveal the role of tea drinking on br...

Read More

Adipogenic progenitors keep muscle stem cells young

10-03-2019

In adult skeletal muscle, loss of myofiber integrity caused by mechanical injuries or diseases are repaired by resident muscle stem cells, called satellite cells, which promptly exit from quiescence after disruption o...

Read More

The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis

10-02-2019

Marrow adipose tissue expansion and associated lipotoxicity are important drivers of age-related bone loss and hematopoietic bone marrow atrophy.

Dr. Gustavo Duque from the Australian Institute for Musculoskele...

Read More

Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging

09-30-2019

For Aging’s Volume 11, Issue 18, the Journal devoted the Cover to a research paper by Dr. Alejandro Martin-Montalvo from the Department of Regeneration and Cell Therapy, Andalusian Ce...

Read More

DNA methylation-based estimator of telomere length

08-25-2019

Leukocyte DNAm TL is applicable across the entire age spectrum and is more strongly associated with age than measured leukocyte TL.

Leukocyte DNAm TL outperforms LTL in predicting: i)time-to-death, ii)time-to-c...

Read More

Epigenome-wide association study of leukocyte telomere length

08-25-2019

In this study, the research team conducted a large-scale epigenome-wide association study of LTL using seven large cohorts the Framingham Heart Study, the Jackson Heart Study, the Womens Health Initiative, the Bogalus...

Read More

‘Tickle’ therapy could help slow ageing

07-30-2019

‘Tickling’ the ear with a small electrical current appears to rebalance the autonomic nervous system for over-55s, potentially slowing down one of the effects of ageing, according to new research.

Scientists fou...

Read More

Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation

06-04-2019

Cessation, or even retardation of the ageing process is an appealing notion that has captured the imagination of humans for millennia. Even if it were possible to rejuvenate our bodies or retard the ageing process, ho...

Read More

Exploiting mitochondrial targeting signal(s), TPP and bis‐TPP, for eradicating cancer stem cells (CSCs)

06-01-2018

TPP-related compounds may provide a novel chemical strategy for effectively targeting bulk cancer cells and CSCs, while minimizing off-target side-effects in normal cells.

Several independent lines of eviden...

Read More

Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype

06-01-2018

The specific molecular mechanism of selective release and retention of senescence-associated sEV-mi RNAs and the EV-SASP cross talk between different cell types and its consequences in the context of aging and age-ass...

Read More

DNA methylation GrimAge strongly predicts lifespan and healthspan

06-01-2018

The Grim Reaper arrives for each of us eventually—wouldn’t it be nice to know when? Now UCLA researchers have developed a new tool to help you plan ahead for your date with the Angel of Death.

Named after ...

Read More

Sex differences in transcriptomic profiles in aged kidney cells of renin lineage (CoRL)

06-01-2018

The researchers found a small core set of genes involved in stemness, proliferation and migration that showed consistent changes with advanced age in cells of renin lineage (CoRL)within the kidney.

Surprisingly...

Read More