Research Paper Volume 4, Issue 12 pp 899—916

Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging

class="figure-viewer-img"

Figure 3. Levels of pS6 and pAKT in the livers of 6 months old females and males. (A) Quantified intensities of pS6 signal in livers of females (n=8) and males 10). Data are mean ± SE. (B) Quantified intensities of p-Akt signal in livers of females (n=8) and males 10). Data are mean ± SE. (C) Correlation between levels of pS6 and p-AKT in livers. (D) Immunohistochemistry. pS6 in the livers of individual males and females. Mice were fasted overnight, then re-fed and sacrificed 2 h later. Bar – 30 μm.