Research Paper Volume 11, Issue 3 pp 950—973

Replicative senescent human cells possess altered circadian clocks with a prolonged period and delayed peak-time

Figure 5. Half-life of luciferase activity is comparable between the proliferative and senescent cells. (A) Representative results of activity decay of luciferase in the proliferative (pro) and senescent (sen) cells are shown. Two independent experiments were performed. (B) Half-life of luciferase activity in the proliferative and senescent cells were quantified. Values are mean ± SEM. p = 0.09; n.s., not significant; n=7, by Student’s two-tailed t test.