Research Paper Volume 11, Issue 6 pp 1619—1632

Cellular retinoic acid binding protein-II expression and its potential role in skin aging

Figure 1. CRABP-II expression is reduced in aged human and mouse skin. (A) Representative images of CRABP-II immunostaining of human normal skin from young/adult and old donors. (B) Bar graphs show semiquantitative evaluation of human epidermal and dermal CRABP-II immunostaining (n=15 young/adult and n=15 old), respectively. (C) Representative images of CRABP-II immunostaining of young/adult and old wild-type mouse skin. (D) Bar graphs show semiquantitative evaluation of mouse epidermal and dermal CRABP-II immunostaining (n=10 young/adult and n=10 old WT). Scale bar: 50µm. Mann-Whitney’s U-test. Abbreviation: AU, arbitrary units.