Research Paper Volume 11, Issue 5 pp 1389—1403

SP1-induced lncRNA TINCR overexpression contributes to colorectal cancer progression by sponging miR-7-5p

Figure 7. TINCR may promote CRC progression via PI3K/Akt/mTOR pathway. (A) miR-7-5p overexpression markedly inhibited the expression of Akt, p-Akt, mTOR and p-mTOR. (B) TINCR upregulation could restore the expression of Akt, p-Akt, mTOR and p-mTOR.