Research Paper Volume 11, Issue 14 pp 5232—5245

Aberrant DNA methylation of synaptophysin is involved in adrenal cortisol-producing adenoma

Figure 1. The expression of SYP in CPA. (A and B) The relative mRNA levels of SYP determined by real-time PCR (A) and protein levels of SYP determined by Western blotting (B) in CPAs and normal adrenal tissues (n=12). (C) Immunohistochemisty staining determines the expression of SYP in CPAs and normal adrenal tissues. The brown area indicated by arrow is the positive staining of SYP in CPAs. Three independent experiments were performed, and representative data are shown. The data represent the mean ± SD. NC, normal control. **p<001.