Research Paper Volume 11, Issue 16 pp 6237—6251

Prognostic value of long non-coding RNA signatures in bladder cancer

Figure 2. (A) Volcano plot of differentially expressed lncRNAs in TCGA-BLCA cohort. (B and C) Venn diagram of prognostic DElncRNAs in prognostic lncRNAs (OS/RFS univariate cox p < 0.05) and DElncRNAs(|logFC| >1 and padj < 0.05). (D) 20-time cross-validation for tuning parameter selection in the LASSO model for OS. (E) LASSO coefficient profiles of 463 prognostic DElncRNAs for OS. (F) 20-time cross-validation for tuning parameter selection in the LASSO model for RFS. (G) LASSO coefficient profiles of 201 prognostic DElncRNAs for RFS.