Research Paper Volume 12, Issue 3 pp 2595—2609

Figure 5. Correlation of Notch expression with immune infiltration level in GC. (A) Notch1 expression had significant positive correlations with infiltrating levels of CD4+ T cells (n = 415). (B) Notch2 expression had significant correlations with infiltrating levels of CD4+ T cells, macrophages, neutrophils, and dendritic cells in GC (n = 415). (C) Notch3 expression was significantly related to infiltrating levels of CD4+ T cells and macrophages in GC but no significant correlation with infiltrating level of B cells (n = 415). (D) Notch4 expression had significant positive correlations with infiltrating levels of CD4+ T cells and macrophages in GC (n = 415). Spearman’s correlation was used to analyze correlation between Notch receptors and immune cells.