Research Paper Volume 12, Issue 4 pp 3574—3593

SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway

Figure 4. Analysis of the prognostic significance of SERPINH1 mRNA levels in GC patients. (A) Patients with high SERPINH1 mRNA levels show significantly poorer OS than patients with low SERPINH1 mRNA levels in the TCGA-STAD dataset (N=388, HR=1.49, P=0.0198). (B) Patients with high SERPINH1 mRNA levels show poorer RFS than patients with low SERPINH1 mRNA levels in the TCGA-STAD dataset (N=324, HR=1.89, P=0.015). (C) GC patients with high SERPINH1 mRNA levels show poorer OS than the GC patients with low SERPINH1 levels in the Kaplan-Meier Plotter database (N=876, HR=1,56, P<0.0001). (D) GC patients with high SERPINH1 mRNA levels show poorer PFS than GC patients with low SERPINH1 levels in the Kaplan-Meier Plotter database (N=641, HR=1.73, P<0.0001).