Research Paper Volume 12, Issue 6 pp 5031—5047

Expression and prognosis analysis of TET family in acute myeloid leukemia

Figure 6. Molecular signatures associated with TET3 in AML. (A) Expression heatmap of differentially expressed genes between TET3low and TET3high AML patients (FDR<0.05, P<0.05 and |log2 FC|>1.5). (B) Volcano plot of differentially expressed genes between TET3low and TET3high AML patients. (C) Gene Ontology analysis of DEGs conducted using online website of STRING (http://string-db.org). (D) Venn results of microRNAs which could target TET3 predicted by DIANA (http://diana.imis.athena-innovation.gr/DianaTools/index.php? r=microT_CDS/index), miRDB (http://mirdb.org/miRDB/), mirDIP (http://ophid.utoronto.ca/mirDIP/), TargetScan (http://www.targetscan. org/vert_72/), and miRWalk (http://mirwalk.umm.uni-heidelberg.de/).