Research Paper Volume 13, Issue 2 pp 1859—1871

Development of prognostic signature based on immune-related genes in muscle-invasive bladder cancer: bioinformatics analysis of TCGA database

Differentially expressed immune-related genes of bladder cancer from the TCGA database (TCGA-BLCA). Heatmap (A) and volcano plot (C) demonstrating differentially expressed genes between bladder tumor and non-tumor tissues, green dots represent down-regulated expressed genes and red dots represent up-regulated expressed genes. Differentially expressed immune-related genes (IRGs) are shown in heatmap (B) and volcano plot (D), green dots represent down-regulated expressed genes and red dots represent up-regulated expressed genes (FDRfilter = 0.05, LogFCfilter = 1).

Figure 1. Differentially expressed immune-related genes of bladder cancer from the TCGA database (TCGA-BLCA). Heatmap (A) and volcano plot (C) demonstrating differentially expressed genes between bladder tumor and non-tumor tissues, green dots represent down-regulated expressed genes and red dots represent up-regulated expressed genes. Differentially expressed immune-related genes (IRGs) are shown in heatmap (B) and volcano plot (D), green dots represent down-regulated expressed genes and red dots represent up-regulated expressed genes (FDRfilter = 0.05, LogFCfilter = 1).